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Table 2 Summary of meta-analysis of the included studies

From: Efficacy of pharmacological intervention for smokeless tobacco cessation in adults: a systematic review and meta-analysis

Outcome or Subgroup

Studies

Participants

Statistical method

Effect estimate

1.1 Abstinence at 3 months

16

3533

Odds Ratio (M-H, Random, 95% CI)

1.54 [1.28, 1.85]

2.1 Abstinence at 6 months

15

3271

Odds Ratio (M-H, Random, 95% CI)

1.21 [1.03, 1.43]

3.1 Abstinence at treatment endpoints(bupropion SR)

3

363

Odds Ratio (M-H, Random, 95% CI)

1.18 [0.51, 2.73]

4.1 Abstinence at treatment endpoints (varenicline)

3

744

Odds Ratio (M-H, Random, 95% CI)

1.99 [1.48, 2.68]

5.1 Abstinence at treatment endpoints (nicotine gum)

3

337

Odds Ratio (M-H, Random, 95% CI)

1.64 [0.82, 3.37]

6.1 Abstinence at treatment endpoints (nicotine patch

4

706

Odds Ratio (M-H, Random, 95% CI)

1.46 [1.07, 1.98]

7.1 Abstinence at treatment endpoints(nicotine lozenge)

6

1630

Odds Ratio (M-H, Random, 95% CI)

1.41 [1.08, 1.83]

  1. * M-H = Mantel Haenszel method, Random = Random effects model, CI = Confidence Interval